Effects of montelukast on M2-related cytokine and chemokine in M2 macrophages
نویسندگان
چکیده
منابع مشابه
Effects of montelukast on M2-related cytokine and chemokine in M2 macrophages.
BACKGROUND/PURPOSE Asthma is a chronic airway inflammatory disease mediated by T-helper (Th)2 cells. Montelukast (trade name Singulair) is a cysteinyl leukotriene receptor antagonist used for asthma treatment. Mirroring Th1-Th2 polarization, two distinct states of macrophages have been recognized: the classically activated (M1) macrophages and the alternatively activated (M2) macrophages. M2 po...
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چکیده ندارد.
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Introduction. Macrophages are key players in complex biological processes. In response to environmental signals, macrophages undergo polarization towards a proinflammatory (M1) or anti-inflammatory (M2) phenotype. Sphingosine 1-phosphate (S1P) is a bioactive lysophospholipid that acts via 5 G-protein coupled receptors (S1P1-5) in order to influence a broad spectrum of biological processes. This...
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In this Article, there are errors in the labelling of the x axis in Fig. 5g,h that were introduced during the production process. The second label on the x axis of each graph in Fig. 5g should have been ‘FWT’ instead of ‘FKO’. In Fig. 5h, the labels ‘0’, ’5’, ’10’ and ‘0’ should have been ‘0‘, ‘1’, ’5’ and ‘10’, respectively. In addition, lane labels indicating the duration of leucine stimulati...
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ژورنال
عنوان ژورنال: Journal of Microbiology, Immunology and Infection
سال: 2018
ISSN: 1684-1182
DOI: 10.1016/j.jmii.2016.04.005